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>   首页   >   产品   >   一抗   >   癌症   >   Rabbit Anti-beta III Tubulin Polyclonal Antibody   

Rabbit Anti-beta III Tubulin Polyclonal Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - Rabbit Anti-beta III Tubulin Polyclonal Antibody AP52263
    L1 rat brain lysates L2 rat kidney lysates probed with Anti TUBB3 Polyclonal Antibody, Unconjugated (AP52263) at 1:200 overnight at 4˚C. Followed by conjugation to secondary antibody at 1:3000 for 90 min at 37˚C. Predicted band 50kD. Observed band size:50kD.
  • 14 - Rabbit Anti-beta III Tubulin Polyclonal Antibody AP52263
    Formalin-fixed and paraffin embedded rat brain labeled with Anti-TUBB3 Polyclonal Antibody, Unconjugated (AP52263) at 1:200 followed by conjugation to the secondary antibody and DAB staining
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF, ICC, IHC-P
Primary Accession Q13509
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 50433 Da
Additional info
Gene ID 10381
Other Names CDCBM; FEOM3; TUBB4; CDCBM1; CFEOM3; beta-4; CFEOM3A; Tubulin beta-3 chain; Tubulin beta-4 chain; Tubulin beta-III; TUBB3
Dilution WB~~1:100~1:500
IHC-P~~1:100~1:500
Format0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Protein Information
Name TUBB3
Synonyms TUBB4
Function Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance.
Cellular Location Cytoplasm, cytoskeleton.
Tissue Location Expression is primarily restricted to central and peripheral nervous system. Greatly increased expression in most cancerous tissues.
Research Areas

BACKGROUND

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance.

REFERENCES

Ranganathan S.,et al.Biochim. Biophys. Acta 1395:237-245(1998).
Banerjee A.,et al.Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
Katsetos C.D.,et al.J. Child Neurol. 18:851-866(2003).
Katsetos C.D.,et al.J. Child Neurol. 19:531-531(2004).

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