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>   首页   >   产品   >   一抗   >   精选抗体   >   G蛋白偶联受体抗体(GPCR)   >   Rabbit Anti-APJ Receptor Polyclonal Antibody   

Rabbit Anti-APJ Receptor Polyclonal Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - Rabbit Anti-APJ Receptor Polyclonal Antibody AP52194
    Mouse heart lysates probed with Rabbit Anti-APJ Receptor Polyclonal Antibody, Unconjugated (AP52194) at 1:300 overnight at 4˚C. Followed by conjugation to secondary antibody at 1:500 for 90 min at 37˚C.
  • 4 - Rabbit Anti-APJ Receptor Polyclonal Antibody AP52194
    Mouse splenocytes probed with Rabbit Anti-APJ Receptor Polyclonal Antibody, Unconjugated (AP52194) at 1:100 for 30 minutes followed by incubation with a FITC conjugated secondary (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange).
  • 14 - Rabbit Anti-APJ Receptor Polyclonal Antibody AP52194
    Formalin-fixed and paraffin-embedded : rat ovary tissue labeled with Rabbit Anti-APELIN RECEPTOR Polyclonal Antibody, Unconjugated(AP52194) 1:200 followed by conjugation to the secondary antibody and DAB staining
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF, IHC-P
Primary Accession P35414
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 42660 Da
Additional info
Gene ID 187
Other Names APJ; APJR; HG11; AGTRL1; Apelin receptor; Angiotensin receptor-like 1; G-protein coupled receptor APJ; G-protein coupled receptor HG11; APLNR
Dilution WB~~1:100~1:500
FC~~1:20~1:100
IHC-P~~1:100~1:500
Format0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Protein Information
Name APLNR
Synonyms AGTRL1, APJ
Function Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon
Research Areas

BACKGROUND

Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. During heart formation, acts as a receptor for elabela hormone (ELA). Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

REFERENCES

O'Dowd B.F.,et al.Gene 136:355-360(1993).
Eggerickx D.,et al.Submitted (JUN-1995) to the EMBL/GenBank/DDBJ databases.

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