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>   首页   >   产品   >   一抗   >   癌症   >   Rabbit Anti-Cytochrome P450 17A1 Polyclonal Antibody   

Rabbit Anti-Cytochrome P450 17A1 Polyclonal Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - Rabbit Anti-Cytochrome P450 17A1 Polyclonal Antibody AP52080
    Lane 1: rat brain lysates Lane 2:rat heart lysates probed with Anti P45017A1/Cytochrome P450 17A1 Polyclonal Antibody, Unconjugated (AP52080) at 1:200 in 4˚C. Followed by conjugation to secondary antibody at 1:3000 90min in 37˚C. Predicted band 56kD. Observed band size: 56kD.
  • 14 - Rabbit Anti-Cytochrome P450 17A1 Polyclonal Antibody AP52080
    Formalin-fixed and paraffin embedded human cervical cancer labeled with Anti P45017A1 Polyclonal Antibody,Unconjugated (AP52080) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
  • 1 - Rabbit Anti-Cytochrome P450 17A1 Polyclonal Antibody AP52080
    Lane 1:rat brain lysates probed with Rabbit Anti-Cytochrome P450 17A1 Polyclonal Antibody, Unconjugated (AP52080) at 1:300 overnight at 4˚C. Followed by conjugation to secondary antibody at 1:5000 for 90 min at 37˚C.
  • 1 - Rabbit Anti-Cytochrome P450 17A1 Polyclonal Antibody AP52080
    Mouse Testis lysates probed with Rabbit Anti-Cytochrome P450 17A1 Polyclonal Antibody, Unconjugated (AP52080) at 1:300 overnight at 4˚C. Followed by a conjugated secondary antibody at 1:5000 for 90 min at 37˚C.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF, IHC-P
Primary Accession P05093
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 57371 Da
Additional info
Gene ID 1586
Other Names CPT7; CYP17; S17AH; P450C17; Steroid 17-alpha-hydroxylase/17, 20 lyase; 17-alpha-hydroxyprogesterone aldolase; CYPXVII; Cytochrome P450 17A1; Cytochrome P450-C17; Cytochrome P450c17; Steroid 17-alpha-monooxygenase; CYP17A1
Dilution WB~~1:100~1:500
IHC-P~~1:100~1:500
Format0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Protein Information
Name CYP17A1
Synonyms CYP17, S17AH
Function Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.
Cellular Location Membrane.
Research Areas

BACKGROUND

Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.

REFERENCES

Chung B.-C.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:407-411(1987).
Picado-Leonard J.,et al.DNA 6:439-448(1987).
Bradshaw K.D.,et al.Mol. Endocrinol. 1:348-354(1987).
Brentano S.T.,et al.Mol. Endocrinol. 4:1972-1979(1990).
Kagimoto M.,et al.Mol. Endocrinol. 2:564-570(1988).

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