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>   首页   >   产品   >   一抗   >   癌症   >   Rabbit Anti-Wide Spectrum Cytokeratin Polyclonal Antibody   

Rabbit Anti-Wide Spectrum Cytokeratin Polyclonal Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - Rabbit Anti-Wide Spectrum Cytokeratin Polyclonal Antibody AP52071
    Lane 1: mouse embryo lysates Lane 2: rat brain lysates probed with Anti CK14/17/42/10 Polyclonal Antibody, Unconjugated at 1:3000 90min in 37˚C. Predicted band 52kD. Observed band size: 52kD.
  • 14 - Rabbit Anti-Wide Spectrum Cytokeratin Polyclonal Antibody AP52071
    Formalin-fixed and paraffin embedded rat skin tissue labeled with Anti-CK14 Polyclonal Antibody, Unconjugated(AP52071) at 1:200 followed by conjugation to the secondary antibody and DAB staining
  • 14 - Rabbit Anti-Wide Spectrum Cytokeratin Polyclonal Antibody AP52071
    Formalin-fixed and paraffin embedded rat articular cartilage tissue labeled with Anti-CK14 Polyclonal Antibody, Unconjugated(AP52071) at 1:300 followed by conjugation to the secondary antibody and DAB staining
  • 8 - Rabbit Anti-Wide Spectrum Cytokeratin Polyclonal Antibody AP52071
    Formalin-fixed and paraffin embedded human epithelial cells tissue labeled with Anti-CK14 Polyclonal Antibody, Unconjugated(AP52071) at 1:300 followed by conjugation to the secondary antibody and DAB staining
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF, ICC, IHC-P
Primary Accession P02533
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Additional info
Gene ID 3861
Other Names K14; NFJ; CK14; EBS3; EBS4; Keratin, type I cytoskeletal 14; Cytokeratin-14; CK-14; Keratin-14; KRT14
Dilution WB~~1:100~1:500
IHC-P~~1:100~1:500
ICC~~1:100~1:500
Format0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Protein Information
Name KRT14
Function The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
Cellular Location Cytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern
Tissue Location Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen.
Research Areas

BACKGROUND

The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.

REFERENCES

Marchuk D.,et al.Cell 39:491-498(1984).
Marchuk D.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:1609-1613(1985).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Zody M.C.,et al.Nature 440:1045-1049(2006).
Hanukoglu I.,et al.Cell 31:243-252(1982).

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