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>   首页   >   产品   >   一抗   >   精选抗体   >   G蛋白偶联受体抗体(GPCR)   >   GPR17 Antibody   

GPR17 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - GPR17 Antibody AP51947
    Anti-GPR17 Antibodyat 1:1000 dilution + human kidney lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 41 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q13304
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 41 KDa
Additional info
Gene ID 2840
Other Names Uracil nucleotide/cysteinyl leukotriene receptor, UDP/CysLT receptor, G-protein coupled receptor 17, P2Y-like receptor, R12, GPR17
Target/Specificity KLH conjugated synthetic peptide derived from human GPR17
Dilution WB~~ 1:1000
Format 0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name GPR17
Function Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain
Research Areas

BACKGROUND

Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.

REFERENCES

Raport C.J.,et al.J. Leukoc. Biol. 59:18-23(1996).
Blaesius R.H.,et al.J. Neurochem. 70:1357-1365(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Ciana P.,et al.EMBO J. 25:4615-4627(2006).

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