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>   首页   >   产品   >   一抗   >   神经科学   >   SCN2B Antibody   

SCN2B Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - SCN2B Antibody AP51861
    Anti-SCN2B Antibody at 1:1000 dilution + 293T/17 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 24 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession O60939
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 24 KDa
Additional info
Gene ID 6327
Other Names Sodium channel subunit beta-2, SCN2B
Target/Specificity KLH conjugated synthetic peptide derived from human SCN2B
Dilution WB~~ 1:1000
Format 0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name SCN2B
Function Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Brain specific.
Research Areas

BACKGROUND

Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier (By similarity).

REFERENCES

Eubanks J.,et al.NeuroReport 8:2775-2779(1997).
Bolino A.,et al.Eur. J. Hum. Genet. 6:629-634(1998).
Cruz J.S.,et al.Science 284:711-711(1999).
Isom L.L.,et al.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).

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