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>   首页   >   产品   >   一抗   >   癌症   >   TIMP4 Antibody   

TIMP4 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - TIMP4 Antibody AP51565
    All lanes : Anti-TIMP4 Antibody at 1:1000 dilution Lane 1: human heart lysates Lane 2: MCF-7 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 26 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q99727
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 26 KDa
Additional info
Gene ID 7079
Other Names Metalloproteinase inhibitor 4, Tissue inhibitor of metalloproteinases 4, TIMP-4, TIMP4
Target/Specificity KLH conjugated synthetic peptide derived from human TIMP4
Dilution WB~~ 1:1000
Format 0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name TIMP4
Function Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP- 9.
Cellular Location Secreted.
Tissue Location Abundant in heart and present at low levels in many other tissues
Research Areas

BACKGROUND

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP- 9.

REFERENCES

Greene J.,et al.J. Biol. Chem. 271:30375-30380(1996).
Olson T.M.,et al.Genomics 51:148-151(1998).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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