|Reactivity||Human, Mouse, Rat|
|Calculated MW||45 KDa|
|Other Names||Serpin B4, Leupin, Peptidase inhibitor 11, PI-11, Squamous cell carcinoma antigen 2, SCCA-2, SERPINB4, PI11, SCCA2|
|Target/Specificity||KLH conjugated synthetic peptide derived from human Serpin B4|
|Format||0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||May act as a protease inhibitor to modulate the host immune response against tumor cells.|
|Cellular Location||Cytoplasm. Note=Seems to also be secreted in plasma by cancerous cells but at a low level|
|Tissue Location||Squamous cells.|
May act as a protease inhibitor to modulate the host immune response against tumor cells.
Barnes R.C.,et al.FEBS Lett. 373:61-65(1995).
Schneider S.S.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:3147-3151(1995).
Hamada K.,et al.Biochim. Biophys. Acta 1518:124-131(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bienvenut W.V.,et al.Submitted (FEB-2008) to UniProtKB.