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>   首页   >   产品   >   一抗   >   细胞生物学   >   RIT1 Antibody   

RIT1 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - RIT1 Antibody AP51476
    Anti-RIT1 Antibodyat 1:1000 dilution + Hela whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 25 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q92963
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 25 KDa
Additional info
Gene ID 6016
Other Names GTP-binding protein Rit1, Ras-like protein expressed in many tissues, Ras-like without CAAX protein 1, RIT1, RIBB, RIT, ROC1
Target/Specificity KLH conjugated synthetic peptide derived from human RIT1
Dilution WB~~ 1:1000
Format 0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name RIT1
Synonyms RIBB, RIT, ROC1
Function Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF- dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.
Cellular Location Cell membrane.
Tissue Location Expressed in many tissues.
Research Areas

BACKGROUND

Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF- dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.

REFERENCES

Lee C.H.J.,et al.J. Neurosci. 16:6784-6794(1996).
Wes P.D.,et al.EMBO J. 15:5839-5848(1996).
Kawasaki H.,et al.Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
Shao H.,et al.Arch. Biochem. Biophys. 371:207-219(1999).
Puhl H.L. III,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.

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