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Defensin alpha 1 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - Defensin alpha 1 Antibody AP51161
    Anti-Defensin alpha 1 Antibody at 1:1000 dilution + huamn spleen lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 10 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P59665
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 10 KDa
Additional info
Gene ID 1667;728358
Other Names Neutrophil defensin 1, Defensin, alpha 1, HNP-1, HP-1, HP1, HP 1-56, Neutrophil defensin 2, HNP-2, HP-2, HP2, DEFA1, DEF1, DEFA2, MRS
Target/Specificity KLH conjugated synthetic peptide derived from human Defensin alpha 1
Dilution WB~~ 1:1000
Format 0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name DEFA1
Synonyms DEF1, DEFA2, MRS
Function Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.
Cellular Location Secreted.
Research Areas

BACKGROUND

Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.

REFERENCES

Daher K.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:7327-7331(1988).
Mars W.M.,et al.Blood 71:1713-1719(1988).
Wiedemann L.M.,et al.Leukemia 3:227-234(1989).
Mars W.M.,et al.J. Biol. Chem. 270:30371-30376(1995).
Linzmeier R.,et al.FEBS Lett. 321:267-273(1993).

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