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Cytochrome P450 2J2 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - Cytochrome P450 2J2 Antibody AP51147
    All lanes : Anti-Cytochrome P450 2J2 Antibody at 1:2000 dilution Lane 1: A549 whole cell lysates Lane 2: A431 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 58 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P51589
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 57 KDa
Additional info
Gene ID 1573
Other Names Cytochrome P450 2J2, Arachidonic acid epoxygenase, CYPIIJ2, CYP2J2
Target/Specificity KLH conjugated synthetic peptide derived from human Cytochrome P450 2J2
Dilution WB~~ 1:2000
Format 0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name CYP2J2
Function This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools.
Cellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein
Tissue Location Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney
Research Areas

BACKGROUND

This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools.

REFERENCES

Wu S.,et al.J. Biol. Chem. 271:3460-3468(1996).
Wu S.,et al.Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
King L.M.,et al.Mol. Pharmacol. 61:840-852(2002).

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