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p18 INK4c Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - p18 INK4c Antibody AP51074
    Anti-p18 INK4c Antibody at 1:1000 dilution + Hela whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 18 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P42773
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 18 KDa
Additional info
Gene ID 1031
Other Names Cyclin-dependent kinase 4 inhibitor C, Cyclin-dependent kinase 6 inhibitor, p18-INK4c, p18-INK6, CDKN2C, CDKN6
Target/Specificity KLH conjugated synthetic peptide derived from human p18 INK4c
Dilution WB~~ 1:1000
Format 0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name CDKN2C
Synonyms CDKN6
Function Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.
Tissue Location Highest levels found in skeletal muscle. Also found in pancreas and heart
Research Areas

BACKGROUND

Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.

REFERENCES

Guan K.-L.,et al.Genes Dev. 8:2939-2952(1994).
Blais A.,et al.Biochem. Biophys. Res. Commun. 247:146-153(1998).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Venkataramani R.,et al.Nat. Struct. Biol. 5:74-81(1998).
Li J.,et al.Biochemistry 38:2930-2940(1999).

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