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ACTN2 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - ACTN2 Antibody AP50959
    All lanes : Anti-ACTN2 Antibody at 1:1000 dilution Lane 1: Hela whole cell lysates Lane 2: human skeletal muscle lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 104 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P35609
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 103 KDa
Additional info
Gene ID 88
Other Names Alpha-actinin-2, Alpha-actinin skeletal muscle isoform 2, F-actin cross-linking protein, ACTN2
Target/Specificity KLH conjugated synthetic peptide derived from human ACTN2
Dilution WB~~ 1:1000
Format 0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name ACTN2
Function F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Cellular Location Cytoplasm, myofibril, sarcomere, Z line Note=Colocalizes with MYOZ1 and FLNC at the Z-lines of skeletal muscle
Tissue Location Expressed in both skeletal and cardiac muscle.
Research Areas

BACKGROUND

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.

REFERENCES

Beggs A.H.,et al.J. Biol. Chem. 267:9281-9288(1992).
Tiso N.,et al.Biochem. Biophys. Res. Commun. 265:256-259(1999).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Faulkner G.,et al.J. Cell Biol. 146:465-475(1999).

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