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ABCG1 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - ABCG1 Antibody AP50949
    Anti-ABCG1 Antibodyat 1:1000 dilution + MCF-7 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 76 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P45844
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 110 KDa
Additional info
Gene ID 9619
Other Names ATP-binding cassette sub-family G member 1, ATP-binding cassette transporter 8, White protein homolog, ABCG1, ABC8, WHT1
Target/Specificity KLH conjugated synthetic peptide derived from human ABCG1
Dilution WB~~ 1:1000
Format 0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name ABCG1
Synonyms ABC8, WHT1
Function Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages.
Cellular Location Mitochondrion. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Predominantly localized in the intracellular compartments mainly associated with the endoplasmic reticulum (ER) and Golgi membranes
Tissue Location Expressed in several tissues. Expressed in macrophages; expression is increased in macrophages from patients with Tangier disease.
Research Areas

BACKGROUND

Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages.

REFERENCES

Chen H.M.,et al.Am. J. Hum. Genet. 59:66-75(1996).
Berry A.,et al.Genomics 68:22-29(2000).
Porsch-Oezcueruemez M.,et al.J. Biol. Chem. 276:12427-12433(2001).
Lorkowski S.,et al.Biochem. Biophys. Res. Commun. 280:121-131(2001).
Kennedy M.A.,et al.J. Biol. Chem. 276:39438-39447(2001).

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