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AQP4 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - AQP4 Antibody AP50937
    Western blot analysis of lysates from mouse RAW264.7,Hela,rat PC-12,U-87 MG cell line (from left to right), using AQP4 Antibody(AP50937). AP50937 was diluted at 1:500 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysates at 20ug per lane.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P55087
Reactivity Human, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 35,32 KDa
Additional info
Gene ID 361
Other Names Aquaporin-4, AQP-4, Mercurial-insensitive water channel, MIWC, WCH4, AQP4
Dilution WB~~ 1:500
Format Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 52% glycerol
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name AQP4
Function Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Brain - muscle >> heart, kidney, lung, and trachea
Research Areas
Atorvastatin ameliorates early brain injury through inhibition of apoptosis and ER stress in a rat model of subarachnoid hemorrhage.
Author : Qi W1,Cao D1,Li Y1,Peng A1,Wang Y1,Gao K1,Tao C1,Wu Y2.
Biosci Rep. 2018 Mar 28. pii: BSR20171035. doi: 10.1042/BSR20171035. [Epub ahead of print]
29592873

BACKGROUND

Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.

REFERENCES

Yang B.,et al.J. Biol. Chem. 270:22907-22913(1995).
Misaka T.,et al.FEBS Lett. 381:208-212(1996).
Lu M.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:10908-10912(1996).
Nusbaum C.,et al.Nature 437:551-555(2005).
Lanciotti A.,et al.Hum. Mol. Genet. 21:2166-2180(2012).

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