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SLC24A4 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - SLC24A4 Antibody AP50838
    Western blot analysis of lysate from human lung tissue lysate,using SLC24A4 Antibody, was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q8NFF2
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality polyclonal
Calculated MW 69,62,67,53 KDa
Additional info
Gene ID 123041
Other Names Sodium/potassium/calcium exchanger 4, Na(+)/K(+)/Ca(2+)-exchange protein 4, Solute carrier family 24 member 4, SLC24A4, NCKX4
Dilution WB~~ 1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name SLC24A4
Synonyms NCKX4
Function Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived. May play a role in calcium transport during amelogenesis (By similarity).
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:Q8NFF2}. Membrane {ECO:0000250|UniProtKB:Q8NFF2}; Multi-pass membrane protein
Tissue Location Expressed abundantly in all regions of the brain, aorta, lung and thymus. Expressed at lower levels in the stomach and intestine
Research Areas

BACKGROUND

Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived. May play a role in calcium transport during amelogenesis (By similarity).

REFERENCES

Li X.-F.,et al.J. Biol. Chem. 277:48410-48417(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Heilig R.,et al.Nature 421:601-607(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

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