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AIBP Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - AIBP Antibody AP50837
    Western blot analysis of lysate from Hela cell line,using AIBP Antibody, was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
  • 3 - AIBP Antibody AP50837
    Immunofluorescence analysis of A549 cells, using AIBP antibody.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF
Primary Accession Q8NCW5
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality polyclonal
Calculated MW 32,20 KDa
Additional info
Gene ID 128240
Other Names NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159}, Apolipoprotein A-I-binding protein {ECO:0000255|HAMAP-Rule:MF_03159}, AI-BP {ECO:0000255|HAMAP-Rule:MF_03159}, NAD(P)HX epimerase {ECO:0000255|HAMAP-Rule:MF_03159}, YjeF N-terminal domain-containing protein 1, YjeF_N1, APOA1BP {ECO:0000255|HAMAP-Rule:MF_03159}
Dilution WB~~ 1:1000
IF~~1:100
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name APOA1BP {ECO:0000255|HAMAP-Rule:MF_03159}
Function Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
Cellular Location Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03159}. Secreted {ECO:0000255|HAMAP-Rule:MF_03159, ECO:0000269|PubMed:11991719}. Note=In sperm, secretion gradually increases during capacitation. {ECO:0000255|HAMAP-Rule:MF_03159}
Tissue Location Ubiquitously expressed, with highest levels in kidney, heart and liver. Present in cerebrospinal fluid and urine but not in serum from healthy patients. Present in serum of sepsis patients (at protein level).
Research Areas

BACKGROUND

Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity).

REFERENCES

Ritter M.,et al.Genomics 79:693-702(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).

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