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ES8L1 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - ES8L1 Antibody AP50836
    Western blot analysis of lysate from human breast tissue lysate,using ES8L1 Antibody, was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
  • 2 - ES8L1 Antibody AP50836
    Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using ES8L1 antibody.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC
Primary Accession Q8TE68
Reactivity Human, Mouse
Host Rabbit
Clonality polyclonal
Calculated MW 82,66,62,56 KDa
Additional info
Gene ID 54869
Other Names Epidermal growth factor receptor kinase substrate 8-like protein 1, EPS8-like protein 1, Epidermal growth factor receptor pathway substrate 8-related protein 1, EPS8-related protein 1, EPS8L1, DRC3, EPS8R1
Dilution WB~~ 1:1000
IHC~~1:50~100
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name EPS8L1
Synonyms DRC3, EPS8R1
Function Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.
Cellular Location Cytoplasm.
Tissue Location Detected in placenta.
Research Areas

BACKGROUND

Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.

REFERENCES

Wu K.,et al.Zhonghua Yi Xue Yi Chuan Xue Za Zhi 16:325-327(1999).
Tocchetti A.,et al.Genomics 81:234-244(2003).
Wan D.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).

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