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TOR1AIP1 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - TOR1AIP1 Antibody AP50777
    Western blot analysis of lysates from Hela,MCF-7 cell line (from left to right),using TOR1AIP1 Antibody(AP50777). AP50777 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q5JTV8
Reactivity Human
Host Rabbit
Clonality polyclonal
Calculated MW 66,43 KDa
Additional info
Gene ID 26092
Other Names Torsin-1A-interacting protein 1, Lamin-associated protein 1B, LAP1B, TOR1AIP1, LAP1
Dilution WB~~ 1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name TOR1AIP1
Synonyms LAP1
Function Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.
Cellular Location Nucleus inner membrane; Single-pass membrane protein
Research Areas

BACKGROUND

Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina (By similarity).

REFERENCES

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Kondo Y.,et al.Biochem. Biophys. Res. Commun. 294:770-778(2002).
Goodchild R.E.,et al.J. Cell Biol. 168:855-862(2005).

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