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>   首页   >   产品   >   一抗   >   神经科学   >   KCNT1 Antibody   

KCNT1 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - KCNT1 Antibody AP50772
    Western blot analysis of lysate from human brain tissue lysate,using KCNT1 Antibody(AP50772). AP50772 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
  • 2 - KCNT1 Antibody AP50772
    Immunohistochemistry analysis of paraffin-embedded human brain tissue using KCNT1 antibody.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC
Primary Accession Q5JUK3
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality polyclonal
Calculated MW 138,142,140 KDa
Additional info
Gene ID 57582
Other Names Potassium channel subfamily T member 1, KCa41, KCNT1, KIAA1422
Dilution WB~~ 1:1000
IHC~~1:50-100
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name KCNT1
Synonyms KIAA1422
Function Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro) (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Highest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle
Research Areas

BACKGROUND

Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro) (By similarity).

REFERENCES

Humphray S.J.,et al.Nature 429:369-374(2004).
Nagase T.,et al.DNA Res. 7:65-73(2000).
Heron S.E.,et al.Nat. Genet. 44:1188-1190(2012).
Barcia G.,et al.Nat. Genet. 44:1255-1259(2012).

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