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B3GALTL Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - B3GALTL Antibody AP50766
    Western blot analysis of lysates from human testis and uterus tissue lysate(from left to right),using B3GALTL Antibody(AP50766). AP50766 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
  • 2 - B3GALTL Antibody AP50766
    Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using B3GALTL antibody.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC
Primary Accession Q6Y288
Reactivity Human
Host Rabbit
Clonality polyclonal
Calculated MW 57 KDa
Additional info
Gene ID 145173
Other Names Beta-1, 3-glucosyltransferase, Beta3Glc-T, 241-, Beta-3-glycosyltransferase-like, B3GALTL, B3GTL
Dilution WB~~ 1:1000
IHC~~1:50-100
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name B3GALTL
Synonyms B3GTL
Function O-fucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.
Cellular Location Endoplasmic reticulum membrane {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:16899492}; Single-pass type II membrane protein
Tissue Location Widely expressed, with highest levels in testis and uterus.
Research Areas

BACKGROUND

O-fucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.

REFERENCES

Heinonen T.Y.K.,et al.Biochem. Biophys. Res. Commun. 309:166-174(2003).
Sato T.,et al.Glycobiology 16:1194-1206(2006).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham A.,et al.Nature 428:522-528(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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