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>   首页   >   产品   >   一抗   >   细胞生物学   >   LZTR1 Antibody   

LZTR1 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - LZTR1 Antibody AP50731
    Western blot analysis of lysate from Hela cell line,using LZTR1 Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q8N653
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 95 KDa
Additional info
Gene ID 8216
Other Names Leucine-zipper-like transcriptional regulator 1, LZTR-1, LZTR1, TCFL2
Dilution WB~~ 1:1000
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name LZTR1 {ECO:0000303|PubMed:7633402, ECO:0000312|HGNC:HGNC:6742}
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates ubiquitination of Ras (K-Ras/KRAS, N-Ras/NRAS and H-Ras/HRAS), leading to inhibit Ras signaling by decreasing Ras association with membranes (PubMed:30442762, PubMed:30442766). Probably mediates non- degradative ubiquitination of Ras (PubMed:30442762).
Cellular Location Endomembrane system Recycling endosome. Golgi apparatus
Research Areas

BACKGROUND

Probable transcriptional regulator that may play a crucial role in embryogenesis.

REFERENCES

Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Kurahashi H.,et al.Hum. Mol. Genet. 4:541-549(1995).
Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).

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