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>   首页   >   产品   >   一抗   >   其他   >   ERF Antibody   

ERF Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - ERF Antibody AP50713
    Western blot analysis of lysate from human ovary tissue lysate,using ERF Antibody(AP50713). AP50713 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
  • 2 - ERF Antibody AP50713
    Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ERF antibody.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC
Primary Accession P50548
Reactivity Human, Mouse
Host Rabbit
Clonality polyclonal
Calculated MW 59 KDa
Additional info
Gene ID 2077
Other Names ETS domain-containing transcription factor ERF, Ets2 repressor factor, PE-2, ERF
Dilution WB~~1:1000
IHC~~1:50-100
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name ERF
Function Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment (By similarity). May be important for regulating trophoblast stem cell differentiation (By similarity).
Cellular Location Nucleus.
Tissue Location Highest levels in testis, ovary, pancreas, and heart.
Research Areas

BACKGROUND

Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment (By similarity). May be important for regulating trophoblast stem cell differentiation (By similarity).

REFERENCES

Sgouras D.N.,et al.EMBO J. 14:4781-4793(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Grimwood J.,et al.Nature 428:529-535(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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