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>   首页   >   产品   >   一抗   >   其他   >   UNG Antibody   

UNG Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - UNG Antibody AP50664
    Western blot analysis of lysates from human heart and skeletal muscle tissue lysate (from left to right),using UNG Antibody(AP50664). AP50664 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P13051
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality polyclonal
Calculated MW 35 34 KDa
Additional info
Gene ID 7374
Other Names Uracil-DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_03166}, UDG {ECO:0000255|HAMAP-Rule:MF_03166}, 32227 {ECO:0000255|HAMAP-Rule:MF_03166}, UNG {ECO:0000255|HAMAP-Rule:MF_03166}
Dilution WB~~1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name UNG {ECO:0000255|HAMAP-Rule:MF_03166}
Function Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
Cellular Location Isoform 1: Mitochondrion.
Tissue Location Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells
Research Areas

BACKGROUND

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

REFERENCES

Olsen L.C.,et al.EMBO J. 8:3121-3125(1989).
Haug T.,et al.FEBS Lett. 353:180-184(1994).
Nilsen H.,et al.Nucleic Acids Res. 25:750-755(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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