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>   首页   >   产品   >   一抗   >   癌症   >   FGF13 Antibody   

FGF13 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - FGF13 Antibody AP50639
    Western blot analysis of lysate from human heart tissue lysate,using FGF13 Antibody(AP50639). AP50639 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q92913
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality polyclonal
Calculated MW 28,22,29,26 KDa
Additional info
Gene ID 2258
Other Names Fibroblast growth factor 13, FGF-13, Fibroblast growth factor homologous factor 2, FHF-2, FGF13, FHF2
Dilution WB~~1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name FGF13
Synonyms FHF2
Function Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus.
Cellular Location Cell projection, filopodium. Cell projection, growth cone. Cell projection, dendrite. Nucleus Cytoplasm. Note=Not secreted Isoform 2: Cytoplasm. Nucleus.
Tissue Location Ubiquitously expressed. Predominantly expressed in the nervous system.
Research Areas

BACKGROUND

Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. May also play a role in MAPK signaling.

REFERENCES

Smallwood P.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:9850-9857(1996).
Gecz J.,et al.Hum. Genet. 104:56-63(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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