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>   首页   >   产品   >   一抗   >   心血管   >   HBP1 Antibody   

HBP1 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - HBP1 Antibody AP50584
    Western blot analysis of lysate from Y79 cell line,using HBP1 Antibody(AP50584). AP50584 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession O60381
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality polyclonal
Calculated MW 58, 51 KDa
Additional info
Gene ID 26959
Other Names HMG box-containing protein 1, HMG box transcription factor 1, High mobility group box transcription factor 1, HBP1
Dilution WB~~ 1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name HBP1
Function Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267, ECO:0000269|PubMed:10562551}
Research Areas

BACKGROUND

Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

REFERENCES

Lemercier C.,et al.Mol. Cell. Biol. 20:6627-6637(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Zhuma T.,et al.EMBO J. 18:6396-6406(1999).

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