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>   首页   >   产品   >   一抗   >   代谢   >   TRXR2 Antibody   

TRXR2 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - TRXR2 Antibody AP50191
    Western blot analysis of lysate from Hela cell line,using TRXR2 Antibody(C0378). C0378 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
  • 2 - TRXR2 Antibody AP50191
    Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using TRXR2 antibody.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC
Primary Accession Q9NNW7
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality polyclonal
Calculated MW 57, KDa
Additional info
Gene ID 10587
Other Names Thioredoxin reductase 2, mitochondrial, Selenoprotein Z, SelZ, TR-beta, Thioredoxin reductase TR3, TXNRD2, KIAA1652, TRXR2
Dilution WB~~ 1:500-1:1000
IHC~~1:50-1:100
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name TXNRD2
Synonyms KIAA1652, TRXR2
Function Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling.
Cellular Location Mitochondrion.
Tissue Location Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low
Research Areas

BACKGROUND

Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling.

REFERENCES

Sun Q.-A.,et al.J. Biol. Chem. 274:24522-24530(1999).
Gasdaska P.Y.,et al.FEBS Lett. 442:105-111(1999).
Miranda-Vizuete A.,et al.Eur. J. Biochem. 261:405-412(1999).
Toji S.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Lescure A.,et al.J. Biol. Chem. 274:38147-38154(1999).

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