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>   首页   >   产品   >   一抗   >   细胞生物学   >   AP2C Antibody   

AP2C Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - AP2C Antibody AP50077
    Western blot analysis of lysate from ZR-75-1 cell line,using AP2C Antibody(C11429). C11429 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q92754
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality polyclonal
Calculated MW 49 KDa
Additional info
Gene ID 7022
Other Names Transcription factor AP-2 gamma, AP2-gamma, Activating enhancer-binding protein 2 gamma, Transcription factor ERF-1, TFAP2C
Dilution WB~~ 1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name TFAP2C
Function Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
Cellular Location Nucleus.
Research Areas

BACKGROUND

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.

REFERENCES

Williamson J.A.,et al.Genomics 35:262-264(1996).
McPherson L.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:4342-4347(1997).
Haselton M.D.,et al.Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
Deloukas P.,et al.Nature 414:865-871(2001).
Nishizawa M.,et al.Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.

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