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>   首页   >   产品   >   一抗   >   心血管   >   FA13A (Cleaved-Gly39) Antibody   

FA13A (Cleaved-Gly39) Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - FA13A (Cleaved-Gly39) Antibody AP50064
    Western blot analysis of lysates from A431,NCI-H1299 cell line (from left to right),using FA13A (Cleaved-Gly39) Antibody(L0206). L0206 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P00488
Reactivity Human
Host Rabbit
Clonality polyclonal
Calculated MW 83 KDa
Additional info
Gene ID 2162
Other Names Coagulation factor XIII A chain, Coagulation factor XIIIa, Protein-glutamine gamma-glutamyltransferase A chain, Transglutaminase A chain, F13A1, F13A
Dilution WB~~1:500- 1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name F13A1
Synonyms F13A
Function Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Cellular Location Cytoplasm. Secreted. Note=Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma
Research Areas

BACKGROUND

Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.

REFERENCES

Ichinose A.,et al.Biochemistry 25:6900-6906(1986).
Grundmann U.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:8024-8028(1986).
Ichinose A.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:5829-5833(1988).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).

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