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>   首页   >   产品   >   一抗   >   精选抗体   >   G蛋白偶联受体抗体(GPCR)   >   Thrombin Receptor Antibody   

Thrombin Receptor Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - Thrombin Receptor Antibody AP50051
    Western blot analysis of lysates from K562 cell line ,using Thrombin Receptor Antibody(C0344). C0344 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P25116
Reactivity Human
Host Rabbit
Clonality polyclonal
Calculated MW 47 KDa
Additional info
Gene ID 2149
Other Names Proteinase-activated receptor 1, PAR-1, Coagulation factor II receptor, Thrombin receptor, F2R, CF2R, PAR1, TR
Dilution WB~~1:500- 1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name F2R
Synonyms CF2R, PAR1, TR
Function High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Platelets and vascular endothelial cells.
Research Areas

BACKGROUND

High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.

REFERENCES

Vu T.-K.H.,et al.Cell 64:1057-1068(1991).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Shapiro M.J.,et al.J. Biol. Chem. 271:32874-32880(1996).
Kahn M.L.,et al.J. Clin. Invest. 103:879-887(1999).
Zania P.,et al.J. Pharmacol. Exp. Ther. 328:378-389(2009).

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