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>   首页   >   产品   >   一抗   >   癌症   >   PHKB Antibody   

PHKB Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - PHKB Antibody AP50043
    Western blot analysis of lysates from K562,Jurkat cell line (from left to right),using PHKB Antibody(C11458). C11458 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q93100
Reactivity Human, Mouse
Host Rabbit
Clonality polyclonal
Calculated MW 125124 Da
Additional info
Gene ID 5257
Other Names Phosphorylase b kinase regulatory subunit beta, Phosphorylase kinase subunit beta, PHKB
Dilution WB~~1:500- 1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name PHKB
Function Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
Cellular Location Cell membrane; Lipid-anchor; Cytoplasmic side
Research Areas

BACKGROUND

Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.

REFERENCES

Wuellrich-Schmoll A.,et al.Eur. J. Biochem. 238:374-380(1996).
Beausoleil S.A.,et al.Nat. Biotechnol. 24:1285-1292(2006).
Daub H.,et al.Mol. Cell 31:438-448(2008).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Oppermann F.S.,et al.Mol. Cell. Proteomics 8:1751-1764(2009).

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