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>   首页   >   产品   >   一抗   >   精选抗体   >   G蛋白偶联受体抗体(GPCR)   >   PAR4 Antibody   

PAR4 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - PAR4 Antibody AP50034
    Western blot analysis of lysates from Hela,Jurkat cell line (from left to right),using PAR4 Antibody(G939). G939 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
  • 3 - PAR4 Antibody AP50034
    Immunofluorescence analysis of LOVO cells, using PAR4 antibody.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF
Primary Accession Q96RI0
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality polyclonal
Calculated MW 41 KDa
Additional info
Gene ID 9002
Other Names Proteinase-activated receptor 4, PAR-4, Coagulation factor II receptor-like 3, Thrombin receptor-like 3, F2RL3, PAR4
Dilution WB~~ 1:1000
IF~~1:100
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name F2RL3
Synonyms PAR4
Function Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets
Research Areas

BACKGROUND

Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.

REFERENCES

Kahn M.L.,et al.J. Biol. Chem. 273:23290-23296(1998).
Kahn M.L.,et al.Nature 394:690-694(1998).
Xu W.-F.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:6642-6646(1998).
King M.M.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
Kahn M.L.,et al.J. Clin. Invest. 103:879-887(1999).

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