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>   首页   >   产品   >   一抗   >   信号转导   >   HS1 Antibody (Ab-397)    

HS1 Antibody (Ab-397)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - HS1 Antibody (Ab-397)  AP50022
    Western blot analysis of lysates from RajI,Daudi cell line (from left to right),using HS1 Antibody (Ab-397) (B8462). B8462 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
  • 1 - HS1 Antibody (Ab-397)  AP50022
    Western blot analysis of extracts from JK cells, using HS1 (Ab-397) Antibody. The lane on the left is treated with synthesized peptide.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P14317
Reactivity Human
Host Rabbit
Clonality polyclonal
Calculated MW 54 KDa
Additional info
Gene ID 3059
Other Names Hematopoietic lineage cell-specific protein, Hematopoietic cell-specific LYN substrate 1, LckBP1, p75, HCLS1, HS1
Dilution WB~~ 1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name HCLS1
Synonyms HS1
Function Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
Cellular Location Membrane; Peripheral membrane protein Cytoplasm. Mitochondrion
Tissue Location Expressed only in tissues and cells of hematopoietic origin
Research Areas

BACKGROUND

Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.

REFERENCES

Kitamura D.,et al.Nucleic Acids Res. 17:9367-9379(1989).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Muzny D.M.,et al.Nature 440:1194-1198(2006).

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