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>   首页   >   产品   >   一抗   >   精选抗体   >   磷酸化抗体   >   Phospho-ARHGAP35(Y1105) antibody   

Phospho-ARHGAP35(Y1105) antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - Phospho-ARHGAP35(Y1105) antibody AP3903a
    Western blot analysis of lysates from A431 cell line, untreated or treated with EGF, 100ng/ml, using Phospho-HUMAN-ARHGAP35(Y1105)(Cat. #AP3903a)(upper) or Beta-actin (lower).
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q9NRY4
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 170514 Da
Additional info
Gene ID 2909
Other Names Rho GTPase-activating protein 35, Glucocorticoid receptor DNA-binding factor 1, Glucocorticoid receptor repression factor 1, GRF-1, Rho GAP p190A, p190-A, ARHGAP35, GRF1, GRLF1, KIAA1722
Target/Specificity This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1090-1135 amino acids from human.
Dilution WB~~1:500
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPhospho-ARHGAP35(Y1105) antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARHGAP35
Synonyms GRF1, GRLF1, KIAA1722
Function Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5'- GAGAAAAGAAACTGGAGAAACTC-3'. May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as a tumor suppressor.
Cellular Location Cytoplasm. Nucleus
Research Areas

BACKGROUND

Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5'- GAGAAAAGAAACTGGAGAAACTC-3'. May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as a tumor suppressor.

REFERENCES

Nagase T.,et al.DNA Res. 7:347-355(2000).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Tikoo A.,et al.Gene 257:23-31(2000).
LeClerc S.,et al.J. Biol. Chem. 266:17333-17340(1991).

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