- 文献引用 : 1
|Application ||IHC-P-Leica, WB, E|
|Calculated MW||41528 Da|
|Other Names||Wnt inhibitory factor 1, WIF-1, WIF1|
|Target/Specificity||This WIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 347-376 amino acids from the C-terminal region of human WIF1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||WIF1 Antibody(Human C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.|
Author : Zhu D1,2,Yang Z3,Liu Z3,Zou Q4,Yuan Y4,Hu C1.
Oncol Lett. 2017 Apr;13(4):2244-2252. doi: 10.3892/ol.2017.5704. Epub 2017 Feb 8.
Provided below are standard protocols that you may find useful for product applications.
WNT proteins are extracellular signaling molecules involved in the control of embryonic development. WIF1 is a secreted protein, which binds WNT proteins and inhibits their activities. This protein contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. It may be involved in mesoderm segmentation. This protein is found to be present in fish, amphibia and mammals.
Elston,M.S., Endocrinology 149 (3), 1235-1242 (2008)
Clement,G., Cancer Sci. 99 (1), 46-53 (2008)
Chan,S.L., Lab. Invest. 87 (7), 644-650 (2007)