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SLC14A2 Antibody (N-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - SLC14A2 Antibody (N-Term) AP22353a
    Anti-SLC14A2 Antibody (N-Term) at 1:500 dilution + Human testis lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 101 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - SLC14A2 Antibody (N-Term) AP22353a
    All lanes : Anti-SLC14A2 Antibody (N-Term) at 1:500 dilution Lane 1: 293T/17 whole cell lysate Lane 2: Human brain lysate Lane 3: K562 whole cell lysate 293T/17 whole cell lysate at 30 µg per lane. H. brain lysate at 50 µg per lane. K562 whole cell lysate at 40 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 101 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q15849
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 101209 Da
Additional info
Gene ID 8170
Other Names Urea transporter 2, Solute carrier family 14 member 2, Urea transporter, kidney, SLC14A2, HUT2, UT2
Target/Specificity This SLC14A2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 42-76 amino acids from the human region of human SLC14A2.
Dilution WB~~1:500
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSLC14A2 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC14A2
Synonyms HUT2, UT2
Function Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism.
Cellular Location Apical cell membrane; Multi-pass membrane protein
Tissue Location Isoform 1 and isoform 2 are expressed in the inner medulla of the kidney.
Research Areas

BACKGROUND

Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism.

REFERENCES

Olives B.,et al.FEBS Lett. 386:156-160(1996).
Bagnasco S.M.,et al.Am. J. Physiol. 281:F400-F406(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Nusbaum C.,et al.Nature 437:551-555(2005).
Mistry A.C.,et al.J. Biol. Chem. 282:30097-30106(2007).

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