|Application ||FC, WB, E|
|Calculated MW||20996 Da|
|Other Names||Glutathione peroxidase 7, GPx-7, GSHPx-7, 188.8.131.52, CL683, GPX7, GPX6|
|Target/Specificity||This GPX7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 73-107 amino acids from the Central region of human GPX7.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GPX7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks.|
|Tissue Location||Expressed in esophageal epithelial cells; expression is up-regulated after exposure to acidic bile acids|
It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks.
Gu S.,et al.Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Barrow I.K.-P.,et al.Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.