|Application ||IF, FC, WB, E|
|Calculated MW||24010 Da|
|Other Names||Grancalcin, GCA, GCL|
|Target/Specificity||This GCA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 19-53 amino acids from the human region of human GCA.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GCA Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.|
|Cellular Location||Cytoplasm. Cytoplasmic granule membrane; Peripheral membrane protein; Cytoplasmic side. Note=Primarily cytosolic in the absence of calcium or magnesium ions. Relocates to granules and other membranes in response to elevated calcium and magnesium levels|
|Tissue Location||Detected in neutrophils and macrophages (at protein level). Highly expressed in bone marrow|
Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.
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Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
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Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.