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>   首页   >   产品   >   一抗   >   精选抗体   >   G蛋白偶联受体抗体(GPCR)   >   GRM2 Antibody (C-Term)   

GRM2 Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - GRM2 Antibody (C-Term) AP22322b
    Anti-GRM2 Antibody (C-Term) at 1:2000 dilution + Human cerebellum lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 96 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q14416
Other Accession P31421
Reactivity Human
Predicted Rat
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 95568 Da
Additional info
Gene ID 2912
Other Names Metabotropic glutamate receptor 2, mGluR2, GRM2, GPRC1B, MGLUR2
Target/Specificity This GRM2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 681-715 amino acids from the human region of human GRM2.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGRM2 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRM2
Synonyms GPRC1B, MGLUR2
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, synapse. Cell projection, dendrite
Tissue Location Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain.
Research Areas

BACKGROUND

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.

REFERENCES

Flor P.J.,et al.Eur. J. Neurosci. 7:622-629(1995).
Yasuyuki F.,et al.Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
Bonner T.I.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Kaighin V.A.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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