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>   首页   >   产品   >   一抗   >   癌症   >   KIAA1524 Antibody (Center)   

KIAA1524 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - KIAA1524 Antibody (Center) AP22314c
    Anti-KIAA1524 Antibody (Center) at 1:2000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 102 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q8TCG1
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 102185 Da
Additional info
Gene ID 57650
Other Names Protein CIP2A, Cancerous inhibitor of PP2A, p90 autoantigen, KIAA1524, CIP2A
Target/Specificity This KIAA1524 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 537-567 amino acids from the Central region of human KIAA1524.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKIAA1524 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KIAA1524
Synonyms CIP2A
Function Oncoprotein that inhibits PP2A and stabilizes MYC in human malignancies. Promotes anchorage-independent cell growth and tumor formation.
Cellular Location Membrane; Single-pass membrane protein. Cytoplasm Note=Slightly concentrates in the perinuclear region
Tissue Location Expressed at low levels in most of the tissues. Overexpressed in head-and-neck squamous cell carcinomas (HNSCC). Present in liver cancer cells (at protein level)
Research Areas

BACKGROUND

Oncoprotein that inhibits PP2A and stabilizes MYC in human malignancies. Promotes anchorage-independent cell growth and tumor formation.

REFERENCES

Soo Hoo L.,et al.Oncogene 21:5006-5015(2002).
Nagase T.,et al.DNA Res. 7:143-150(2000).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Shi F.D.,et al.Prostate 63:252-258(2005).

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