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MPL Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - MPL Antibody (C-Term) AP22313b
    Anti-MPL Antibody (C-Term) at 1:2000 dilution + Mouse spleen lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 70 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P40238
Other Accession P40931, Q08351
Reactivity Mouse
Predicted Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 71245 Da
Additional info
Gene ID 4352
Other Names Thrombopoietin receptor, TPO-R, Myeloproliferative leukemia protein, Proto-oncogene c-Mpl, CD110, MPL, TPOR
Target/Specificity This MPL antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 514-546 amino acids from the human region of human MPL.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMPL Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MPL
Synonyms TPOR
Function Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed at a low level in a large number of cells of hematopoietic origin. Isoform 1 and isoform 2 are always found to be coexpressed
Research Areas

BACKGROUND

Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses.

REFERENCES

Vigon I.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:5640-5644(1992).
Mignotte V.,et al.Genomics 20:5-12(1994).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Saur S.J.,et al.Blood 115:1254-1263(2010).

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