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>   首页   >   产品   >   一抗   >   癌症   >   TGFA Antibody (C-Term)   

TGFA Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - TGFA Antibody (C-Term) AP22303b
    All lanes : Anti-TGFA Antibody (C-Term) at 1:2000 dilution Lane 1: A431 whole cell lysate Lane 2: HACAT whole cell lysate Lane 3: RPMI 8226 whole cell lysate Lane 4: U-87 MG whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 17 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P01135
Other Accession P48030, Q06922, P01134
Reactivity Human
Predicted Mouse, Pig, Rat
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 17006 Da
Additional info
Gene ID 7039
Other Names Protransforming growth factor alpha, Transforming growth factor alpha, TGF-alpha, EGF-like TGF, ETGF, TGF type 1, TGFA
Target/Specificity This TGFA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 118-150 amino acids from the human region of human TGFA.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTGFA Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TGFA
Function TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
Cellular Location Transforming growth factor alpha: Secreted, extracellular space
Tissue Location Isoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines
Research Areas

BACKGROUND

TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.

REFERENCES

Derynck R.,et al.Cell 38:287-297(1984).
Jakowlew S.B.,et al.Mol. Endocrinol. 2:1056-1063(1988).
Qian J.F.,et al.Gene 132:291-296(1993).
Qian J.F.,et al.Am. J. Hum. Genet. 53:168-175(1993).
Machida J.,et al.Genomics 61:237-242(1999).

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