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RGMB Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - RGMB Antibody AP22293a
    All lanes : Anti-RGMB Antibody at 1:2000 dilution Lane 1: U-251 MG whole cell lysate Lane 2: 293 whole cell lysate Lane 3: Human brain lysate Lane 4: Mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 48 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - RGMB Antibody AP22293a
    All lanes : Anti-RGMB Antibody at 1:2000 dilution Lane 1: 293 whole cell lysate Lane 2: Human brain lysate Lane 3: Mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 48 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q6NW40
Reactivity Human, Mouse
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 47547 Da
Additional info
Gene ID 285704
Other Names RGM domain family member B, DRG11-responsive axonal guidance and outgrowth of neurite, DRAGON, RGMB
Target/Specificity This RGMB antibody is generated from a rabbit immunized with a recombinant protein of human RGMB.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRGMB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RGMB
Function Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor. Membrane raft
Research Areas

BACKGROUND

Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.

REFERENCES

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).
Liu X.,et al.Biochem. Biophys. Res. Commun. 382:795-800(2009).
Bell C.H.,et al.Science 341:77-80(2013).

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