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PTGDR Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - PTGDR Antibody (C-Term) AP22292b
    All lanes : Anti-PTGDR Antibody (C-Term) at 1:2000 dilution Lane 1: HepG2 whole cell lysate Lane 2: Y79 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 40 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q13258
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 40271 Da
Additional info
Gene ID 5729
Other Names Prostaglandin D2 receptor, PGD receptor, PGD2 receptor, Prostanoid DP receptor, PTGDR
Target/Specificity This PTGDR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 306-348 amino acids from human PTGDR.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPTGDR Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTGDR
Function Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in retinal choroid, ciliary epithelium, longitudinal and circular ciliary muscles, iris, small intestine and platelet membranes.
Research Areas

BACKGROUND

Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity).

REFERENCES

Boie Y.,et al.J. Biol. Chem. 270:18910-18916(1995).
Martin A.L.,et al.Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
Heilig R.,et al.Nature 421:601-607(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Town M.H.,et al.Prostaglandins 25:13-28(1983).

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