|Application ||WB, E|
|Calculated MW||11268 Da|
|Other Names||Interferon alpha-inducible protein 27, mitochondrial, p27, Interferon alpha-induced 11.5 kDa protein, Interferon-stimulated gene 12a protein, ISG12(a), IFI27|
|Target/Specificity||This IFI27 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 72-106 amino acids from human IFI27.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IFI27 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9.|
|Cellular Location||Mitochondrion. Membrane; Multi-pass membrane protein|
Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9.
Rasmussen U.B.,et al.Cancer Res. 53:4096-4101(1993).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Parker N.,et al.BMC Genomics 5:8-8(2004).
Rosebeck S.,et al.Apoptosis 13:562-572(2008).