|Application ||WB, E|
|Calculated MW||59572 Da|
|Other Names||Excitatory amino acid transporter 1, Sodium-dependent glutamate/aspartate transporter 1, GLAST-1, Solute carrier family 1 member 3, SLC1A3, EAAT1, GLAST, GLAST1|
|Target/Specificity||This SLC1A3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 127-161 amino acids from human SLC1A3.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC1A3 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||EAAT1, GLAST, GLAST1|
|Function||Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia|
Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
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