|Application ||WB, E|
|Calculated MW||71245 Da|
|Other Names||Thrombopoietin receptor, TPO-R, Myeloproliferative leukemia protein, Proto-oncogene c-Mpl, CD110, MPL, TPOR|
|Target/Specificity||This MPL antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 133-166 amino acids from human MPL.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MPL Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for thrombopoietin that acts as a primary regulator of megakaryopoiesis and platelet production. May represent a regulatory molecule specific for TPO-R-dependent immune responses.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Golgi apparatus. Cell surface|
|Tissue Location||Expressed at a low level in a large number of cells of hematopoietic origin. Isoform 1 and isoform 2 are always found to be coexpressed|
Provided below are standard protocols that you may find useful for product applications.
Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses.
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