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MPL Antibody (N-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - MPL Antibody (N-Term) AP22241a
    All lanes : Anti-MPL Antibody (N-Term) at 1:2000 dilution Lane 1: Daudi whole cell lysate Lane 2: HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 71 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P40238
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 71245 Da
Additional info
Gene ID 4352
Other Names Thrombopoietin receptor, TPO-R, Myeloproliferative leukemia protein, Proto-oncogene c-Mpl, CD110, MPL, TPOR
Target/Specificity This MPL antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 133-166 amino acids from human MPL.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMPL Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MPL
Synonyms TPOR
Function Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed at a low level in a large number of cells of hematopoietic origin. Isoform 1 and isoform 2 are always found to be coexpressed
Research Areas

BACKGROUND

Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses.

REFERENCES

Vigon I.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:5640-5644(1992).
Mignotte V.,et al.Genomics 20:5-12(1994).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Saur S.J.,et al.Blood 115:1254-1263(2010).

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