|Application ||WB, E|
|Other Accession||Q9HAW8, P22309, P35503, P22310, Q28612, P35504, P19224, Q28611, Q9HAW7, Q9HAW9|
|Calculated MW||59941 Da|
|Other Names||UDP-glucuronosyltransferase 1-9, UDPGT 1-9, UGT1*9, UGT1-09, UGT1.9, 220.127.116.11, UDP-glucuronosyltransferase 1-I, UGT-1I, UGT1I, UDP-glucuronosyltransferase 1A9, lugP4, UGT1A9, GNT1, UGT1|
|Target/Specificity||This UGT1A9 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 408-439 amino acids from the human UGT1A9.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||UGT1A9 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1.|
|Cellular Location||Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein|
|Tissue Location||Liver. Isoform 1 and isoform 2 are expressed in liver, kidney, colon, esophagus and small intestine|
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1.
Wooster R.,et al.Biochem. J. 278:465-469(1991).
Ciotti M.,et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
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Hillier L.W.,et al.Nature 434:724-731(2005).
Owens I.S.,et al.Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.