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MAN1C1 Antibody (N-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - MAN1C1 Antibody (N-Term) AP22200a
    Anti-MAN1C1 Antibody (N-Term) at 1:2000 dilution + human brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 71 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q9NR34
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 70911 Da
Additional info
Gene ID 57134
Other Names Mannosyl-oligosaccharide 1, 2-alpha-mannosidase IC, 3.2.1.113, HMIC, Mannosidase alpha class 1C member 1, Processing alpha-1, 2-mannosidase IC, Alpha-1, 2-mannosidase IC, MAN1C1, MAN1A3, MAN1C
Target/Specificity This MAN1C1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 89-120 amino acids from human MAN1C1.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMAN1C1 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAN1C1
Synonyms MAN1A3, MAN1C
Function Involved in the maturation of Asn-linked oligosaccharides. Trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc.
Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location Expressed in most tissues with the exception of lung, muscle and pancreas. Highly expressed in placenta
Research Areas

BACKGROUND

Involved in the maturation of Asn-linked oligosaccharides. Trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc.

REFERENCES

Tremblay L.O.,et al.J. Biol. Chem. 275:31655-31660(2000).
Gregory S.G.,et al.Nature 441:315-321(2006).

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