|Application ||WB, E|
|Calculated MW||109998 Da|
|Other Names||Poly [ADP-ribose] polymerase 10, PARP-10, 22.214.171.124, ADP-ribosyltransferase diphtheria toxin-like 10, ARTD10, PARP10|
|Target/Specificity||This PARP10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 565-597 amino acids from the Central region of human PARP10.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PARP10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in cell proliferation. May be required for the maintenance of cell cycle progression.|
|Cellular Location||Nucleus, nucleolus. Cytoplasm. Note=Shuttles between the nuclear and cytoplasmic compartment. A subpopulation concentrates in the nucleolus during late G1/S phase|
|Tissue Location||Highly expressed in spleen and thymus. Intermediate levels in liver, kidney, pancreas, prostate, testis, ovary, intestine, and leukocytes. Low expression in heart, brain, placenta, lung, skeletal muscle, and colon|
May play a role in cell proliferation. May be required for the maintenance of cell cycle progression.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Yu M.,et al.Oncogene 24:1982-1993(2005).
Chou H.Y.,et al.J. Biol. Chem. 281:15201-15207(2006).
Choudhary C.,et al.Science 325:834-840(2009).